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Scutellaria moniliorrhiza Komarov Labiatae is a perennial he
2024-03-13
Scutellaria moniliorrhiza Komarov (Labiatae) is a perennial herb and mainly distributed in Jilin province, China. In traditional Chinese medicine, the whole plants have been used to clear away heat-evil, expel superficial evils, eliminate stasis and reduce edema (He et al., 2012). In previous phytoc
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EHop-016 Introduction Glaucoma consists of a group of eye
2024-03-13
Introduction Glaucoma consists of a group of eye diseases showing a broad spectrum of clinical presentation and unknown aetiologies, that lead to a permanent loss of visual function due to the death of retinal ganglion EHop-016 and damage of the optical nerve. It is well accepted that a critical ri
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Control of retinal vascularization during development and
2024-03-13
Control of retinal vascularization during development and OIR likely involves close interactions among endothelial cells, neurons and glial UM171 (microglial and astrocytes) (see Fig. 2). In particular, the interaction between endothelial tip cells and astrocytes plays a critical role in developmen
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Adenosine receptors activate a number of
2024-03-13
Adenosine receptors activate a number of signalling pathways involved in tissue survival including several mitogen-activated protein kinases (Fredholm et al., 2001). The common feature of all adenosine receptors is the positive coupling to ERK1/2, whilst A2B and A3 receptors can also activate the st
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Finally Urban Ciecko et al asked whether this
2024-03-12
Finally, Urban-Ciecko et al. (2018) asked whether this enhancement is specific to the pyramidal to SST neuron synapses or more generally observed in other synapses of the cortical microcircuit. Synapses between pyramidal cells showed no sign of potentiation after either bath application of the choli
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Search sphere This sphere includes the acetylcholine binding
2024-03-12
Search sphere 1: This sphere includes the cdc42 pathway binding site between the α–γ subunits. The center point of the search area was located at x=35.26, y=77.67, z=137.74 and the initial search radius was set to 27Å which assures that the corresponding area outside the channel pore of the two subu
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cathepsin g Taniyama et al reported a female with
2024-03-12
Taniyama et al. reported a female with infertility who had a homozygous T-to-A transversion at nucleotide position g.2472 in exon 3 of the CYP17A1 gene (mutation Y201N) and decreased 17-hydroxylase and 17,20-lyase activities of cathepsin g was initiated using dexamethasone to control adrenal P prod
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Aurora B is also known as chromosomal passenger protein
2024-03-12
Aurora-B is also known as chromosomal passenger protein and localizes at the chromosome arms and at centromeres during prophase. As cell cycle continues, Aurora-B moves towards the inner centromere region followed by the central spindle and cortex during glut 1 and finally accumulates in the midbody
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br Removal of therapeutic doses of
2024-03-12
Removal of therapeutic doses of glatiramer acetate from Marek’s Disease Vaccines The impact of this change seems to vary widely among operations, probably dependent on the pre-existing quality of hatching egg production, hatchery sanitation, hatchery management, and brooding management. Increase
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The increased occurrence of ARIA E in
2024-03-12
The increased occurrence of ARIA-E in APOE ε4 carriers in phase 2 studies resulted in separate protocols for carriers and noncarriers in the subsequent phase 3 studies. Two 18-month trials comprising 1121 carriers and 1331 noncarriers with mild to moderate AD tested doses of bapineuzumab that varied
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Here we provide evidence that NO contributes to changes
2024-03-12
Here, we provide evidence that NO contributes to changes in synaptic strength, but also offer an explanation as to why previous attempts to link NO to LTP have often failed. Our results describe a model by which cycling AMPARs, held in intracellular pools, are rapidly delivered to the membrane surfa
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The rescue of the behavioral deficit was associated
2024-03-12
The rescue of the behavioral deficit was associated with a significant reduction in the levels of both soluble and insoluble Aβ peptides and their deposition in the WAY-100635 maleate salt mg of the same animals. In search for the mechanism behind the reduced amyloidosis, we assessed APP metabolism
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br Results br Discussion Many tumor cells rely on
2024-03-12
Results Discussion Many tumor boc boc rely on EAAs to provide fundamental building blocks for macromolecular biosynthesis because they cannot synthesize EAAs de novo (Hattori et al., 2017; Sheen et al., 2011). Therefore, they must use highly effective transporters to maximize EAA uptake from
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A key building block in MT
2024-03-12
A key building block in MT-SGL is the computation of the proximal operator in (12) when is the multi-task sparse group lasso regularizer given byFor MT-SGL, the iterates x ≡ Θ are matrices, and the proximal operator is computed at z ≡ Z = Θ + α(Θ − Θ). For the loss function L(·) corresponding to Ga
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Obesity is defined as a body
2024-03-11
Obesity is defined as a body mass index (BMI) of 30kg/m2 or higher and is known to have a very close association with the risk of developing cancers (Hsueh and Deng, 2016). Several theories exist as to how this link is defined with respect to various cancers, one of which involves the effect of obes
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