• The use of progestogen only methods

  2020-07-29

  

  The use of progestogen-only methods of contraception [progestogen-only contraceptives (POCs)] during the period of lactation has raised concerns for negative effects [7]. Progestogens could interfere with lactogenesis, especially immediately postpartum [8], and have been shown to be transferred to b

• Introduction Maintenance of genome integrity

  2020-07-28

  

  Introduction Maintenance of genome integrity is essential for life, and faithful DNA replication and repair ensure this. One of the most important parameters for DNA maintenance is the regulation of optimal concentrations of the four 5′-deoxyribonucleoside-triphosphates (dNTPs) the precursors for D

• The prokaryotic DgkB from Staphylococcus

  2020-07-28

  

  The prokaryotic DgkB from Staphylococcus aureus is essential for lipoteichoic serine threonine protein kinase synthesis (Matsuoka et al., 2011) and its solubility makes it particularly interesting with respect to its relevance to mammalian DGKs. Importantly, this is the first bona fide DGK with a s

• br Acknowledgments Authors acknowledge financial

  2020-07-28

  

  Acknowledgments Authors acknowledge financial support from the National Natural Science Foundation of China (31402274, 31172389), the Special Project of Marine Renewable Energy from the State Oceanic Administration (SHME2011SW02), China Postdoctoral Science Foundation (2014M551381) and Shanghai U

• br Conclusion Several classes of

  2020-07-28

  

  Conclusion Several EGTA of models have successively emerged since the 1970s. Three main models describing Ca2+ binding to CaM are now surviving: All three models explain most of the experimental results obtained up to now. However, the two first ones, due to the symmetrical behavior of the two

• br Disclosure br Introduction DAP kinase DAPK a

  2020-07-28

  

  Disclosure Introduction DAP-kinase (DAPK), a Ca2+/calmodulin activated Ser/Thr kinase, was originally identified by Adi Kimchi and co-workers at the Weizmann Institute while screening for genes critical for IFN-γ-induced cell death. DAPK belongs to a family of related death kinases, all of whi

• br Experimental br Acknowledgments br

  2020-07-28

  

  Experimental Acknowledgments Phylogenetic analysis was carried out within the framework of the institutional research project (no. 01201255617) of the Komarov Botanical Institute of the Russian Academy of Sciences. Financial support was provided in part by the Russian Foundation for Basic Re

• HU 308 A more detailed description of higher order thinking

  2020-07-28

  

  A more detailed description of higher-order thinking is offered by King, Goodson, and Rohani (1998): “Higher order thinking skills include critical, logical, reflective, metacognitive, and creative thinking. They are activated when individuals encounter unfamiliar problems, uncertainties, questions

• The UI components used in our proposal

  2020-07-28

  

  The UI components used in our proposal are called COTSgets, from COTS (Commercial Off-The-Shelf) [28] and gadgets (understood as any software that can work alone or as a piece of the architecture). A COTS component is any coarse-grained component developed by third parties available for building mor

• No effect on the A

  2020-07-28

  

  No effect on the Aβ production by γ-secretase was observed at 50μM, the highest effective concentration used in cultured ana cas by the study of Flajolet et al. IC261 did also not exert a modulatory effect on the production of Aβ, Aβ and Aβ species in the cell-free assay at this concentration. γ-Se

• Introduction Piperine is a pungent alkaloid

  2020-07-28

  

  Introduction Piperine is a pungent alkaloid and accounts for 2–5% dry weight in black and white peppers (Butt et al., 2013). Physiological benefits of piperine have been a subject of extensive research in recent years. Piperine is an antioxidant with strong anti-inflammatory and antiangiogenic acti

• The potential existence of ER

  2020-07-27

  

  The potential existence of ER stress was first examined in EVTs in placental bed biopsy specimens obtained from pregnancies complicated by early-onset preeclampsia. It was then tested whether ER stress can modulate MMP-2 activity before elucidating the role of proinflammatory cytokines in the induct

• The RING finger and the U box type E

  2020-07-27

  

  The RING-finger and the U-box- type E3 ligases act as a scaffold protein to bridge an E2 enzyme and a substrate proximally for ubiquitin conjugation (Fig. 1). The RING-finger-type E3 ligases are generally thought to be the biggest family of ligases and contain a Zn2+-coordinating domain with spaced

• br Results br Discussion High throughput genome

  2020-07-27

  

  Results Discussion High throughput genome-wide and proteome-wide screens in yeast model host for TBSV have helped tremendously the identification and characterization of host factors subverted for viral replication (Nagy et al., 2014). Follow up experiments using tombusviruses and plants (base

• br Role of funding source

  2020-07-27

  

  Role of funding source This project was funded by the National Natural Science Fund of China (Grant no. 81071082) and Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (Grant no. ZYLY 201403). Contributors Yi-Lang Tang, Wen-Biao Li, Pei-Xia

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