• A pragmatic trial program highlights the tension between

  2018-11-05

  

  A pragmatic trial program highlights the tension between two perspectives of clinical research. In the traditional view, all clinical research puts patients at risk and therefore they must be protected through informed consent. In the pragmatic triallist’s view, the fact that both treatment arms rep

• glibenclamide Methodological advances in bereavement researc

  2018-11-05

  

  Methodological advances in bereavement research in recent years have improved the quality of research outputs, not least through the introduction of the Integrated Risk Factor Framework (IRFF) (Stroebe, Folkman, Hansson, & Schut, 2006). A key feature of this framework is that variables from a number

• However this explanation of stress as a

  2018-11-05

  

  However, this explanation of stress as a direct cause of social disparities in physical health does not account for the fact that socially-disadvantaged groups, particularly African Americans and Hispanics in the US, despite having higher morbidity and mortality, have better mental health relative t

• Previous qualitative studies have found that adult children

  2018-11-05

  

  Previous qualitative studies have found that adult children\'s migration may yield a benefit or a disadvantage for the health outcome of parents ‘left behind’, depending on the specific country context and the nature of the relationship following the migration of the child(ren) (Miltiades, 2002; Vul

• Special Health Care Needs There is at least an

  2018-11-05

  

  There is at least an implicit, and possibly quite real, tradeoff between US public spending for medical care versus other social services—for which US spending is a much smaller portion of GDP than in other OECD nations (Avendano and Kawachi, 2014; Stuckler, Basu, & McKee, 2010). This difference rai

• We agree with the position advocated within all of these

  2018-11-05

  

  We agree with the position advocated within all of these methodological works that a coherent theoretical basis for intervention development, and use of evaluation to test key causal assumptions and build theory, are crucial. Viewing evaluation not simply as a stop/go test of effectiveness, but as a

• In this context companies face the process of building and

  2018-11-05

  

  In this context, companies face the process of building and maintaining relationships that prove to be valuable for both customers and the company. Considering a proposal of integrating the TOE model (Technology–Organization–Environment) and the focus on relationship management applied to the m-mark

• It is with much pride that I

  2018-11-05

  

  It is with much pride that I am able to write the foreword to our first issue of the (SAJCE) published by Elsevier. The Journal was originally published by the South African Institution of Chemical Engineers. I remember receiving copies of the journal by post in the late 1990s as an undergraduate s

• Introduction Raw water in South Africa is considered

  2018-11-05

  

  Introduction Raw water in South Africa is considered a strategic national resource, with the responsibility for its management taking place at three tiers. These are firstly Central Government, secondly Provincial and Regional Governments, including other specified authorities, and thirdly Local Au

• br Materials and methods br Funding source

  2018-11-05

  

  Materials and methods Funding source Results Discussion In this study, we report a global evaluation of the state of activation of the immune, endothelial and coagulation systems in 120 treated patients aviremic for at least 2years. A first conclusion is that these patients overall prese

• As the epidemic expands in scale and

  2018-11-05

  

  As the epidemic expands in scale and geographic range, a growing number of travellers are exporting ZIKV to other regions of the world, including Europe, where Aedes vectors are known to be present (Maria et al., 2016; Zammarchi et al., 2015; http://ecdc.europa.eu/en/healthtopics/vectors/vector-maps

• br Funding This research was funded by the Ministerio de

  2018-11-05

  

  Funding This research was funded by the Ministerio de Economía y Competitividad, project ref. ECO2013-44027-P. Introduction and objectives The market of food and agriculture products and fish products is immersed in a globalisation process and in a more and more competitive environment, with

• In narcolepsy cataplexy there is

  2018-11-05

  

  In narcolepsy–cataplexy, there is an increase in the incidence of REM sleep behavioral disorder (RBD) [77]. In RBD the mechanisms that produce atonia are significantly reduced, which supports the hypothesis that the dysfunction of the hypocretinergic system produces instability of motor regulatory s

• br Stimulation of other regions The region of

  2018-11-05

  

  Stimulation of other regions The region of the PPN is not the only site stimulated to induce changes in arousal [44]. Regions aside from the RAS implicated in the modulation of waking include: (a) the orexin-containing neurons of the lateral hypothalamus, (b) the cholinergic neurons of the basal

• The analysis of age specific recommended sleep durations

  2018-11-05

  

  The analysis of age-specific recommended sleep durations revealed similar results: the significantly highest proportion of patients with non-recommended low sleep duration (43%) was found among patients with SUD (AND 24%; SCZ 10%; c.f. Table 2). No significant gender differences were found with res

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