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Using expression data from teratomas we were able to
2018-10-31
Using expression data from teratomas, we were able to identify a large variety of differentiated tissues within them. This allowed us to analyze a repertoire of differentiated cell types in each embryonic germ layer. Teratomas initiated from PSCs express characteristic genes of all analyzed tissues
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In summary we demonstrated that OCT is
2018-10-31
In summary, we demonstrated that OCT4 is critical for mesendoderm differentiation by showing its involvement in eviction of the PRC2 complex and loss of the H3K27me3 mark from mesendodermal genes. The effect on SOX17 is most revealing as it demonstrates pre-patterning of this gene prior to gene expr
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We sought to determine whether T cell derived iPSCs
2018-10-31
We sought to determine whether T cell-derived iPSCs (TiPSCs) could be used to analyze neurological diseases. Several issues regarding the utilization of TiPSCs in neurological studies remain unresolved. First, previous studies indicated that each iPSC clone retains an epigenetic memory relating to t
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br Introduction Bone marrow derived mesenchymal
2018-10-31
Introduction Bone marrow-derived mesenchymal stromal cell (BM-MSC)-derived osteoblasts and chondrocytes are responsible for bone and cartilage modeling/remodeling, respectively (Harada and Rodan, 2003; Wu et al., 2009). Osteoblasts are defined by lineage-specific transcription factors RUNX2 and O
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br Acknowledgment The study has been sponsored
2018-10-30
Acknowledgment The study has been sponsored by a Russian Science Fund grant (project no. 15-19-00091). Introduction The issue of the flow and heat transfer in cross-flowed tube bundles is among the most practically important ‘canonical’ cases [1,2] of the problem on liquid metal coolant therm
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histone methyltransferase Social cohesion can also be assess
2018-10-30
Social histone methyltransferase can also be assessed as a group-level influence, where it is often operationalized as an average score among individuals within a community or neighbourhood (Andrade et al., 2015; Cradock, Kawachi, Colditz, Gortmaker & Buka, 2009; Fisher, Li, Michael & Cleveland, 20
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While there is a large growing body of quantitative
2018-10-30
While there is a large growing body of quantitative studies on insomnia and its consequences, there are few studies on the subjective experience of insomnia. Using three focus groups sessions, Carry et al. investigated the lived experience of patients with insomnia. They reported that as an unpleasa
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br Conclusions br Introduction Safety concerns
2018-10-30
Conclusions Introduction Safety concerns about food, drinking water, health surveillance, and clinical diagnosis related to microbial pathogens have attracted increasing attention worldwide. On the basis of Discussion structure and stain ability with gram stain (weakly alkaline solution of cry
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We report a new electrochemical biosensor
2018-10-30
We report a new electrochemical biosensor for CRP detection as part of a first step in the development of simple, multi-electrode microfluidic clinical diagnostic tools. One of the biggest challenges with multi-analyte electrochemical biosensors is localization of the affinity agents on individual e
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mecamylamine br Evoluci n de la industria petrolera
2018-10-30
Evolución de la industria petrolera y de la economía mexicanas La mayor parte de los países involucrados escogió el camino de crear por lo menos una empresa petrolera o un ente público nacional fuerte, eficiente y dinámico encargado de la tarea y al servicio del interés nacional: autonomía energé
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Introducci n El art culo se basa en las conclusiones
2018-10-30
Introducción El artículo se basa en las conclusiones obtenidas en el Seminario Semestral organizado por Centro de Estudios Económicos de la Unión Europea-México (ceeuem), sobre la situación económico-social de la Unión Europea (ue); por lo mismo, incorpora algunas discusiones estructurales y los ef
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Before moving on to explain the analysis
2018-10-30
Before moving on to explain the analysis framework and the tools developed, it seems appropriate to briefly underline how the crisis translates into various shocks to the Brazilian economy. As notes Araújo, “the main sphk of transmission of the international crisis for Brazil refer to credit, decre
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It can be inferred that companies innovating and
2018-10-30
It can be inferred that gip receptor companies’ innovating and differentiating products import MT with high technological content and/or interact with foreign manufacturers through special MT orders, whereas those that are specialized in standardized products—most part of the users—use medium sophi
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Several ongoing clinical trials are evaluating the feasibili
2018-10-30
Several ongoing clinical trials are evaluating the feasibility of combining chemotherapeutic nanomedicines with radiotherapy or small molecule drugs (such as gemcitabine). Pegylated liposomal doxorubicin has shown improved therapeutic efficacy when combined with radiotherapy in several animal studie
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ambroxol hydrochloride Following detection of CRA surveillan
2018-10-30
Following detection of CRA, surveillance colonoscopy after 3years is strongly recommended (Lieberman et al., 2012), and this was reinforced by the recent finding that a 5-year interval was insufficient (Loberg et al., 2014). Our results may help to inform CRA/CRC screening, particularly where referr
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