• Ultimately we decided to investigate the role of Cyp

  2019-07-01

  

  Ultimately, we decided to investigate the role of Cyp3a in obesity because Hepatic P450 Reductase-null (HRN) mice with no P450 activity show hepatic steatosis with increased Cyp2b10 and Cyp3a11 expression, perturbations in liver size, lipid homeostasis, and increased liver polyunsaturated fatty acid

• br Materials and methods br Results br Discussion Adiponecti

  2019-07-01

  

  Materials and methods Results Discussion Adiponectin is one of the most studied adipocytokines. Its release from adipocytes is down-regulated in obesity and other adverse metabolic conditions leading to decreased serum concentrations (Turer and Scherer, 2012). Several factors and conditions

• It was reported that IVM modulates various

  2019-07-01

  

  It was reported that IVM modulates various ion channels, such as type-A GABACls, α7 acetylcholine-gated cation channels, P2X4 ATP-gated cation channels, and glycine-gated chloride blue in vertebrates (Adelsberger et al., 2000, Khakh et al., 1999, Krause et al., 1998, Krůšek and Zemková, 1994, Shan e

• A recent report has shown that C elegans homozygous for

  2019-07-01

  

  A recent report has shown that C. elegans homozygous for a point mutation within the HORMA domain of HTP-1 (M127K), which disrupts its association with chromosome axes, displayed an extended zone of PLK-2 localization to PCs in response to asynapsis (Silva et al., 2014), which, as we show here, is a

• Although the study is of a high quality

  2019-07-01

  

  Although the study is of a high quality given the constraints of the case-control design, we question whether it alone provides sufficient evidence for this policy recommendation. Observational studies of ITNs are notoriously fraught with challenges. Even in settings in which randomised trials show

• Now consider a Special Report by

  2019-07-01

  

  Now consider a Special Report by the WHO Ebola Response Team. In it, the authors rightly—if not tautologically—suggest that shortening the delay to isolation of Ebola virus disease suspects would lead to quicker overall outbreak containment, yet they fail to adequately discuss the reality that suspe

• On the other hand it was also shown that multi

  2019-07-01

  

  On the other hand, it was also shown that multi-fraction long-course radiotherapy results in better re-calcification and fewer recurrences of spinal cord 740 Y-P within the irradiated spinal region [24,25]. In case of recurrence, Nieder et al. [10] reviewed that re-irradiation of the spinal cord to

• In summary current evidence suggests

  2019-07-01

  

  In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in

• br Material and methods br

  2019-07-01

  

  Material and methods Results Discussion Conclusion Financial support Conflicts of interest Introduction Metabolic syndrome comprises a cluster of conditions, including obesity, insulin resistance, hypertension, and abnormal cholesterol levels, which together increase cardiovascu

• Si bien esta amerita un

  2019-07-01

  

  Si bien esta amerita un análisis detallado, me detendré en algunas cuestiones que considero clave para entender el modo en cómo resuelve Vigil la integración del pasado colonial. En primer lugar, aparece ya una clara intención de situar ionophore éste como los orígenes de lo que será la nación mexi

• Findings from the last major systematic review

  2019-07-01

  

  Findings from the last major systematic review of the global prevalence of echocardiographic rheumatic Ketorolac tromethamine salt disease showed that the highest calculated regional prevalence was in sub-Saharan Africa (5·7 cases per 1000 people), indigenous people in the Pacific islands, Austral

• br Discussion IUI with controlled ovarian

  2019-06-29

  

  Discussion IUI with controlled ovarian hyperstimulation has been used over the years as a treatment for mild male factor, anovulation, and unexplained infertility. It is less expensive and less invasive than other assisted reproductive techniques. Therefore, these advantages have made the techniq

• br Risk of bleeding complications

  2019-06-29

  

  Risk of bleeding complications with dual antiplatelet agents Dual antiplatelet therapy (DAPT) with combined aspirin and clopidogrel has become a standard treatment after percutaneous coronary intervention (PCI). Recent studies have examined the impact of such therapy on the incidence of bleeding

• Fmoc-Gly-OH Finally MM patients have accelerated bone loss w

  2019-06-29

  

  Finally, MM patients have accelerated bone loss when compared to age-matched controls. Bone mineral density is decreased in patients with MM as well as in patients with monoclonal gammopathy of undetermined significance (MGUS) [19,20], a clinically benign condition defined by a low level of monoclon

• SR 11302 weight br Conclusion br Conflict of interest br Cas

  2019-06-29

  

  Conclusion Conflict of interest Case report A 65-year-old woman with permanent atrial fibrillation was admitted with diastolic SR 11302 weight failure (HF) secondary to rapid ventricular response. She had undergone single chamber pacemaker implantation (Boston Scientific Ingenio SR) two ye

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