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During the past few years several studies have addressed
2019-07-26

During the past few years, several studies have addressed macrophage phenotype in experimental models, such as angiotensin II-induced AAA. A first study investigated macrophage phenotype using flow cytometry to identify M1 and M2 macrophages and qPCR analysis for expression of NOS2 and Ym1/2. The au
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br Experimental Procedures br Author Contributions br Acknow
2019-07-26

Experimental Procedures Author Contributions Acknowledgments Introduction Germinal centers (GCs) form in secondary lymphoid organs of vertebrates in response to challenge with T-cell-dependent antigens. After extrafollicular and follicular interactions with cognate antigen and T helper c
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In attempts to further purify His Artemis
2019-07-25

In attempts to further purify [His]6-Artemis, numerous matrices were assessed including anion and cation exchange, and SCR7 interaction chromatography. The results from these matrices were universally poor (data not shown). Fractionation via adsorption chromatography on a hydroxyapatite (HAP) matrix
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br Results br Discussion The results
2019-07-25

Results Discussion The results showed a surprising THZ1 for of DNA in stains even at extreme environmental conditions (35–65 °C, 100% relative humidity), provided the stains had been dried prior to incubation. We had expected a rapid decay of DNA at high relative humidity but observed, on the
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Family and twin studies have estimated the heritability of o
2019-07-25

Family and twin studies have estimated the heritability of obesity to be between 40 and 70% [5], [6], [7]. However, all known risk variants can only account for ∼3% of the variance in BMI [8], [9]. Therefore, alternate methods are needed to identify additional risk factors. In recent decades, Drosop
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The field of synthetic cytokine biology continues to grow th
2019-07-25

The field of synthetic cytokine biology continues to grow through molecular, physiological and pathophysiological insights, as well as via new methodical advances. The approval of chimeric antigen receptor (CAR) T cell immunotherapy by the US Food and Drug administration (FDA) in August 2017 for rel
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Opiate withdrawal promotes the activation
2019-07-25

Opiate withdrawal promotes the activation of the corticotropin-releasing factor (CRF) system, a major coordinator of neuroendocrine and behavioral responses to stressors. For instance, early (8–48 h) morphine withdrawal is associated with increased CRF mRNA expression in the central nucleus of the a
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At the same time that the CPA
2019-07-25

At the same time that the CPA education requirements have been increasing, the composition of the post-secondary student population has experienced a substantial increase in the number and relative proportion of students who delay college or university matriculation. These students tend to exhibit a
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CPH models reported usually as lists
2019-07-25

CPH models, reported usually as lists of risk factors along with their parameters, are prevalent in medical literature. One such model is the CPH model created for the purpose of predicting the probability of one year survival of patients suffering from Pulmonary Arterial Hypertension [5]. The model
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The proposed FDIR technique is presented
2019-07-25

The proposed FDIR technique is presented in the following format: Section 2 contains a survey of typical orbits of interest with regard to the TAK-242 for environment found in them, which is contrasted with a LEO orbit. Additionally, how the requirements for the satellite system can be estimated is
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PR957 The aim of the present study was to investigate the
2019-07-25

The aim of the present study was to investigate the acute effects of THC on resting state PR957 neurophysiology, and to examine the impact of COMT genotype on these effects. Thirty-nine healthy volunteers participated in a randomised, placebo-controlled, crossover pharmacological MRI study. Acute e
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Located on the fore tarsals of the front
2019-07-25

Located on the fore-tarsals of the front pair of legs, the Haller’s organ is presumed central to tick chemosensation. Recent genomic, transcriptomic and proteomic investigations have identified several families of transmembrane proteins in the forelegs of ticks that are likely involved in olfactory
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The intestinal cholesterol absorption markers sitosterol and
2019-07-25

The intestinal cholesterol bet bromodomain markers sitosterol and campesterol to cholesterol levels were significantly lower in Villin-Tgif1 mice compared to wild type mice, irrespective of diet. However, the decrease was less pronounced in Villin-Tgif1 mice fed a chow diet (∼20–30%) compared to mi
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br Conclusions br Statement of authorship br
2019-07-25

Conclusions Statement of authorship Nonaneurysmal subarachnoid hemorrhage (NA-SAH) differs from aneurysmal subarachnoid hemorrhage (SAH) in both clinical course and outcome. In spite of many reports and case series since the first description in 1985, the etiology of NA-SAH remains uncertain
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Building s constructional elements should be
2019-07-25

Building\'s constructional elements should be able to protect residents from the negative effect of noise caused by surroundings [19]. The World Health Organization estimates that each year more than one million Healthy Life Years are lost in the European Union member states and other Western Europe
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