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DMPO chemical One possibility to differentiate between the t
2019-07-22
One possibility to differentiate between the two failure modes, and also to identify the corresponding characteristics of the resulting fracture surface, is a series of FNCT measurements with varying nominal (initial) stress. The dependence of the observed time to failure tf on the actual stress cha
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To our knowledge immunohistochemical analysis for proGRP
2019-07-22
To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor BKT140 were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated serum proGRP w
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In order to evaluate the in vivo pharmacology associated wit
2019-07-19
In order to evaluate the in vivo pharmacology associated with EP receptor antagonism, we wished to discover antagonists presenting a higher degree of selectivity over the other prostanoid receptors. We also wanted to increase the brain–blood ratio since it is probable that centrally mediated EP agon
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During the past decade it became increasingly clear that the
2019-07-19
During the past decade, it became increasingly clear that the affinity and efficacy of small agonists acting on the orthosteric binding site of a GPCR can be modulated by ligands that bind to a topographically distinct (allosteric) binding site on the same GPCR molecule 33, 39, 40, 41, 42. This allo
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Herein we further established a dynamic DNA self assembly
2019-07-19
Herein, we further established a dynamic DNA self-assembly activated hemin-mimetic enzymes system by embedding DNA-hemin into an entropy-driven DNA-assembly for fluorescent biosensing. The entropy-driven dynamic DNA-assembly is one of the toehold-mediated isothermal strand displacement reactions, wh
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Our results showed that in
2019-07-19
Our results showed that in elastase-induced AAA, TGF-β neutralization finely tunes macrophage phenotype. Note that several studies have already addressed the role of M1 markers, such as IL-6 and IL-1β, or M2 markers, including IL-10 and TGF-β.4, 9, 10, 11 The expression and the role of ARG1 in AAA h
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br Acknowledgments This work was supported by Grants
2019-07-19
Acknowledgments This work was supported by Grants from the National Research Foundation (2010-0000782) and the National Center for GM Crops (PJ008152) of the Next Generation BioGreen 21 Program funded by the Rural Development Administration, Republic of Korea, to W.T.K. Introduction Ubiquityl
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In the case of the reaction of a with Py
2019-07-19
In the case of the reaction of 1a with Py2SMeCu(II), compound 4a was observed as the major oxidation product suggesting that further oxidation or hydrolysis of 4a was prevented under our conditions. The precise factors that govern the reactivity and stability of nitrosoamidines remain poorly known.
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For radiochemotherapy it is well known that mitotic
2019-07-19
For radiochemotherapy, it is well known that mitotic cell death and apoptosis present the major cell death modes. More recently, autophagy-dependent cell death has been described to occur upon radiochemotherapy (Daido et al., 2005, Song et al., 2017). This form of regulated cell death depends on com
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Fmoc-His(Boc)-OH.CHA where One of the most frequent gene alt
2019-07-19
One of the most frequent gene alterations in MM is methylation of the p15 and p16 genes in the 5′ upstream region. P15 and p16 proteins are Fmoc-His(Boc)-OH.CHA where regulators involved in the inhibition of transition from G1 to S phase. Frequencies of p15 or p16 gene methylation up to 32% and 53
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Although PQQ has nutritional importance and pharmacological
2019-07-18
Although PQQ has nutritional importance and pharmacological effects in higher organisms, including humans [15], until recently, there was no clear evidence for the use of PQQ as a co-factor in a eukaryotic enzyme. This review presents a novel eukaryotic PQQ-dependent quinohemoprotein recently discov
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The study reported here had the primary
2019-07-18
The study reported here had the primary goal to compare the methylation of HPV late genes with methylation of the DAPK promoter, and with histological or cytological diagnoses among high-risk patients that were referred to a colposcopy clinic based on abnormal cervical cytology. Based on the literat
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br Materials and methods br Results As shown in
2019-07-18
Materials and methods Results As shown in Table 1, blood urea nitrogen and serum creatinine levels were significantly elevated at both 1st and 7th days of pyelonephritis, when compared with those of the control group (Pcarboxypeptidase a formation or intratubular neutrophils, while tubules sh
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br Experimental methods br Results
2019-07-18
Experimental methods Results and discussion Conclusions Here we describe the first reported method for high-yield Tadalafil solubility of active and soluble mature CPG2 (in the absence of the leader peptide) and its individual catalytic and dimerization domains in E. coli. Such a method is
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Since inception of the accelerated program in California
2019-07-18
Since inception of the accelerated program in 2000, California has varied the requirements for CPA licensure. Prior to 2002, licensure was available with a bachelor’s degree in any subject, 24 semester hours (36 quarter units) of accounting, 24 semester hours (36 quarter units) of general business,
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